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PhD in Electronics and Nanoscale Engineering - Molecular Spin-Based Quantum Sensors for Biomedical Applications at University of Glasgow

University of Glasgow
Full-time
On-site
GB

Start date: From January 2026

This PhD project aims to develop molecular spin-based quantum sensors for versatile deployment in biomedical applications.

Spin-based quantum sensors exploit optical detection of spin states to measure magnetic fields and other physical quantities—such as temperature and strain—with exceptional sensitivity, down to the single-molecule level. Solid-state crystal defect platforms, such as nitrogen-vacancy (NV) centres in diamond, have demonstrated powerful sensing capabilities due to their ability to be coherently manipulated and sensitively detected, even at room temperature. These systems offer exciting prospects, including nanoscale magnetic resonance imaging, however, they face significant limitations: their properties are fixed by the host material, their integration with external targets is constrained by the crystal matrix, and their spatial arrangement is difficult to control with precision.

This project explores an emerging alternative: molecular quantum sensors—a highly tuneable and flexible class of spin-based quantum systems. Unlike solid-state defects, molecular systems offer intrinsic tunability through chemical design, allowing precise control over their properties. They can be engineered for targeted conjugation to biomolecules and integrated into biological environments, opening new possibilities for quantum biosensing.

This project builds directly on our recent work from the Quantum Optospintronics Group. We have demonstrated the key building blocks of molecular quantum sensing—including optical spin readout, coherent spin control, and room-temperature operation—all realised in chemically synthesised molecules [Phys. Rev. Lett. 133, 120801 (2024)]. Our work also shows how synthetic design can be used to enhance key sensing metrics, such as optical-spin contrast [J. Am. Chem. Soc. 147, 26 (2025)]. These advances lay the foundation for a powerful new sensing platform with wide-ranging potential in the biomedical sciences.

Through this multidisciplinary project, you will gain broad expertise in areas such as electron and nuclear spin resonance, cryogenic and room-temperature optical spectroscopy and quantum-mechanical simulations. The project spans physics, chemistry, biomedicine, and quantum technologies, offering opportunities to engage in cross-disciplinary and international collaborations, including potential travel, contributing to pioneering efforts developing novel quantum sensors.

Application details & further information

We seek a motivated and curious student with a strong interest in quantum technologies, molecular materials, and their application to sensing and biomedical research. The ideal candidate will have:

·      A first class or upper second-class honours degree in Physics, Chemistry, Electronic Engineering, Materials Science, or a related discipline.

·      A relevant Master’s degree is desirable

·      Enthusiasm for working across disciplines at the interface of quantum science, molecular design, and biomedical applications

We are committed to fostering and promoting an inclusive, supportive, and flexible working environment in all our activities. We particularly welcome applications from candidates from groups which have been historically under-represented in STEM subjects/research.

For more information, please see our Quantum Optospintronics Group website.  

To apply, please contact Dr Sarah Mann and Dr Sam Bayliss with:

·      A short statement of motivation outlining your interest and suitability

·      A CV (maximum two pages)

Further details on the application procedure are available at:

http://www.gla.ac.uk/research/opportunities/howtoapplyforaresearchdegree/.